Doxiderol Review 2019 – Pros and Cons

DoxiderolWhat is Doxiderol

Doxiderol is a dietary supplement designed to increase concentration and focus, improve memory, and support better overall cognitive functions. This nutraceutical formula is produced in a GMP certified facility, and it was developed by Mentis Laboratories LLC.

All Mentis Laboratories formulas are advertised as high-quality supplements resulted from rigorous sets of tests which they have to pass before reaching stores’ shelves. To convince its clients about the quality of this formula, Mentis Laboratories claims its production facilities are the subject of third-party audits conducted by NSF International – “The Public Health and Safety Company” twice a year.

Doxiderol Ingredients

Doxiderol’s formula includes the following ingredients: Vitamin B12 (as Cyanocobalamin) 6 mcg, Vitamin B5 (as D-Calcium Pantothenate) 2 mg, and Doxiderol Proprietary Blend (Vinpocetine, Bacopa Monnieri Leaf Extract, Acetyl-L-Carnitine, L-Theanine, Caffeine, and Citicoline) 915 mg.

Other (inactive) ingredients: Magnesium Stearate and Silica.

Benefits of Doxiderol

Doxiderol combines several different herbal extracts with various amino-acids and Citicoline, which is involved in the synthesis of essential brain nutrients and nerve signaling processes. Each of these ingredients was shown to help in the maintenance of brain’s health under various aspects, but we will go into details in the sections below.

Particularly useful for people working in stressful environments, Doxiderol is a well-structured product (in what concerns its chemical composition) as it does not include a large number (often unnecessary) of ingredients. We actually support this approach because the greater the number of components, the higher the chances of adverse interactions between the active chemicals, which in the end means lower safety and even lower potency.

Doxiderol is said to have a positive effect on the blood flow towards and from the brain, information exchange, and neurotransmitters synthesis. Unfortunately, a significant disadvantage of Doxiderol is that it does not provide any scientific evidence that the combination featured here is indeed useful in supporting brain health. In fact, we couldn’t find a list of the exact dosages of each active chemical. A full list of ingredients is available, but it doesn’t show how much of each ingredient was used in the formulation.

Doxiderol combines a total of 8 active substances, namely herbal extracts (Vinpocetine, Bacopa Monnieri, and caffeine), amino acids (Acetyl-L-Carnitine and L-Theanine), Citicoline, and two B-vitamins (B12 and B5).

Vinpocetine is a chemically produced ingredient extracted from the Vinca Minor Periwinkle plant. The main benefits of Vinpocetine come from its peripheral vasodilator ability. This particular quality helps increase cerebral blood flow protects brain cells. In turn, brain functions like memory and concentration are improved. More so, the chemical has been observed to increase the cerebral synthesis of ATP, involved in the processes of energy production and energy transfer.

Vinpocetine has been used both as traditional medicine, and a doctor recommended therapy against cerebrovascular conditions, age-related memory loss, and tinnitus. Although considered to be relatively safe when used as recommended, Vinpocetine may still cause mild to moderate adverse reactions including stomach pain, migraine headache, sleep disturbances, nausea, and nervousness.

Acetyl-L-Carnitine is a chemical naturally produced in the liver and kidneys. Certain foods (such as red meat, poultry, fish, and dairy products) are known to provide increased amounts of Acetyl-L-Carnitine, but people can get a healthy dose of Acetyl-L-Carnitine through supplementation as well.

Classified as powerful amino acid and a building block of proteins, Acetyl-L-Carnitine plays a significant role in numerous functions in the body including in the energy production processes and antioxidant defense.


Clinical evidence suggests ALCAR also possesses important neuroprotective properties, making it potentially helpful in patients who have Alzheimer\\\’s disease, various forms of dementia, Parkinson’s disease, or other memory-related disorders. Acetyl-l-carnitine is considered safe in doses lower than 3 grams per day.

Citicoline is a natural substance, a known precursor of Phosphatidylcholine, a primary compound of cell membranes. It is also used in the synthesis of Acetylcholine, an essential chemical in the brain, particularly crucial to maintaining memory and recall capacity.

The main advantages of this compound derived from its ability to help the body repair and generate healthy brain tissue (also known as gray matter) and maintain adequate amounts of essential nutrients like Acetylcholine and neurotransmitters (Norepinephrine and Dopamine).

Although these ingredients seem to have been the subject of serious clinical investigations, we cannot understand why the amounts are not mentioned. This puts us in an uncomfortable position, very hard to evaluate whether the quantities included can actually offer the marketed benefits.

How Much Does Doxiderol Cost?

Each bottle of Doxiderol contains 30 capsules. The formula’s dosage may vary largely, starting from two capsules and ending up to a maximum of eight capsules per day. Thus, a bottle may supply the necessary amount for 2 to 4 weeks, depending on the dose administered. In this case, the price for a daily serving may vary substantially from $2 – $7.5 (calculated using the price for a two-pack from the official site).

On the same premises, this product may be classified as a moderately priced or as an expensive supplement (if used intensively).

Still, the advantage is that Doxiderol comes with a 90-day money back guarantee, available for both unused and used bottles containing more than 80% of their content. Shipping charges are not included.

Customers who order 2 or more bottles of Doxiderol will benefit from other additional discounts and promotional prices.

Potential Doxiderol Side Effects

There are no potential side effects mentioned on Doxiderol’s official webpage.

However, some of the ingredients used in this formulation have been associated with some potential side effects. For instance, higher doses of Acetyl-L-Carnitine may cause mild side effects like vomiting, rashes, diarrhea, and fishy body odor. High doses of Vinpocetine have been associated with stomach pain, migraine headache, sleep disturbances, nausea, and nervousness.


  • Fair price compared to other similar brain supplements
  • There are many positive reviews available online, particularly from students who are extremely happy with this supplement
  • Fast acting formula – first results should be visible within 30 minutes
  • Mentis Laboratories is a reputable and trustworthy manufacturer with many years of experience on this market
  • A dedicated website with more than enough information about the product


  • Doxiderol doesn’t work for everyone
  • No supplement facts label
  • Not recommended to those who are sensitive to caffeine

Final Verdict

Doxiderol is a good choice in most situations, especially for people who are looking for a natural nootropic stack. Doxiderol can also be a decent alternative to prescription drugs such as Adderall, but the formula may work a lot better when taken with more powerful smart drugs.

Stacking Doxiderol with a compound like Noopept, Piracetam, Adrafinil, or Sunifiram can provide greater cognitive enhancements. These nootropics are known for being a lot more powerful and more efficient at improving learning, focus, memory, and energy.

Check the #1 Best-Selling Brain Supplement in the USA

About Philip Gibson

Ann Olson is a freelance health writer and blogger specializing in diet reviews, sexuality education, disease awareness and healthy eating. She currently writes various health and diet articles for several websites, including eHow, and She also has a history of educating readers about mental and sexual health issues on Associated Content and Yahoo! Voices, where she was a featured health and wellness contributor.