Amoryn Review 2019 – Pros and Cons

AmorynWhat is Amoryn

Amoryn is considered one of the more potent natural antidepressants available on the market at this moment. Developers claim that Amoryn works by addressing the cause of anxiety and depression, making more than just a temporary cover-up of the issue. If that is true, then Amoryn should definitely be one of our top brain supplements.

Amoryn is offered by BioNeurix Corporation, a US-based company that, according to its official website, prides itself by placing a high value on the quality of the supplements they offer. BioNeurix official website describes the company as being focused on developing and producing supplements that are clinically tested and proven to be highly efficient and much safer than anything else available on the market at this moment.

BioNeurix was founded in October 2002, and they released their first product, Amoryn, in 2003. Amoryn was quite successful at that time, and it was quickly followed by several other supplements like Seredyn in 2004 and Mellodyn in 2005.

Amoryn Ingredients

Amoryn includes the following active ingredients: Hyperforin (from 600 mg of St. John’s Wort) 18 mg, 5-HTP 25 mg, Rhodiola Rosea 90 mg, Selenium 70 mcg, Vitamin C 10 mg, Vitamin D3 400 IU, Vitamin B6 20 mg, Vitamin B12 30 mcg, Folate 300 mcg, and Zinc 15 mg.

Inactive ingredients: gelatin, rice powder, and magnesium stearate.

Benefits of Amoryn

Amoryn is promoted as a mood-boosting supplement that contains several well known natural mood enhancers like Hyperforin, Rhodiola Rosea, and 5-HTP. According to BioNeurix, Amoryn is one of the top-selling mood-boosting formulations available on the nutritional supplements market.

Amoryn’s official site claims that this formula is produced under the highest quality regulations and Natural Products Association (NPA) standards and includes clinically proven dosages of the highest purity raw materials.

So does Amoryn actually work? The formula is not unique by any stretch of the imagination, in fact, there are quite a few similar supplements out there. Nevertheless, we like most of the ingredients used in this brain supplement. The collection of herbal compounds included in Amoryn is interesting, and it may be able to boost the body’s natural mood-lifting chemicals.


Hyperforin (a derivative of the very popular herb known as St. John’s Wort) probably is the key ingredient here. The plant has been traditionally used to reduce symptoms of depression and anxiety, and it seems to exhibit fewer side effects than standard medication. Recent clinical evidence appears to support some of the claims behind this derivative. It seems that Hyperforin has reuptake inhibitory properties, which allows it to modify the levels of neurotransmitters in the brain. Neurotransmitters are prevented from being reabsorbed into the brain so that they will remain available for longer periods of time. It is believed that, in time, Hyperforin can prevent depletion of these essential chemicals that would otherwise cause an adverse psychological impact.

The problem we have with Hyperforin is its reduced capacity to cross the brain blood barrier (BBB). This is a standard issue with all herbal extracts, and it can have a substantial impact on their effectiveness.

Amoryn also contains a small dose of 5-HTP, an extract of the Griffonia plant which directly stimulates the release of serotonin and keeps serotonin levels balanced. The process through which 5-HTP turns into serotonin is through its decarboxylation in the presence of proper amounts of Vitamin B6. Some amounts of the resulted serotonin may remain in the peripheral parts of the body, but it has been shown that significant amounts manage to reach the brain, which is the actual purpose of 5-HTP.

From what we can see, each key ingredient used here may be effective at lifting the mood – when they are available in the proper quantities. But we have some worries regarding these amounts. The typical therapeutic dose for 5-HTP is 100 to 300 mg, three times a day. There is only 25 mg of 5-HTP in one Amoryn serving. Hyperforin and St. John’s Wort is usually recommended at 300 mg, three times per day. Amoryn only contains 18 mg of Hyperforin per serving. Many consumers reported almost no benefits of taking this supplement, and the very small dose of the primary ingredients may explain why.

How Much Does Amoryn Cost?

One bottle of Amoryn contains 60 capsules, which should be enough for one full month of treatment at a recommended dose of 2 capsules per day. The list price for a 60 capsules bottle is $34.95.

BioNeurix offers an AutoShip option as well. By choosing to use the AutoShip feature, you can save $5 per bottle. We recommend caution because this option falls under a Terms & Conditions policy.

Amoryn can be purchased directly from BioNeurix official website, through a secure ordering page that accepts VISA, American Express, Maestro, Mastercard, and PayPal as payment options. You can also purchase the supplement from various online retailers (like the one we suggested below) that can offer additional discounts and even free shipping within the United States.

Potential Amoryn Side Effects

According to BioNeurix, “most people do not experience any negative side effects when taking Amoryn.” However, they also state that the above claim is based on non-scientific surveys of Amoryn consumers. As for listed potential side effects, the only one we could find on the official website is an increased skin sensitivity due to the inclusion of Hyperforin. Our online research has revealed that some consumers complained about high blood pressure.


  • 10+ years on the market
  • Amoryn is produced by a reputable company
  • The formula consists of a mix of very powerful ingredients
  • Cheaper than other similar brain supplements
  • Many positive reviews and testimonials available online
  • Widely available online and offline


  • Some key ingredients are in very low amounts and might not be as effective as advertised
  • Amoryn’s formula is not unique by any means
  • Some of the company’s claims are not supported by any real clinical evidence

Final Verdict

Amoryn is one of those products we find difficult to rank. The formula has been around, unchanged, for a very long time and there are plenty of positive reviews and testimonials online. The official website looks good and it provides enough information to the user of the average supplement.

The formula appears to have the right ingredients, which is another plus. But we feel that the quantities of each ingredient are not there. 25 mg of 5-HTP and 18 mg of Hyperforin is way below the typical therapeutic dose, and this might be the reason why many consumers have complained about poor results upon using this brain supplement.

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About Philip Gibson

Ann Olson is a freelance health writer and blogger specializing in diet reviews, sexuality education, disease awareness and healthy eating. She currently writes various health and diet articles for several websites, including eHow, and She also has a history of educating readers about mental and sexual health issues on Associated Content and Yahoo! Voices, where she was a featured health and wellness contributor.